It is largely unknown, but throughout its history Berlin was also an important center of chemistry. Particularly during the development of the phlogiston theory in the first half of the 18th century and in the time of August Wilhelm Hofmann and Emil Fischer between around 1865 and 1920, Berlin can even be viewed as the most important international center of chemistry. The chemical industry was also once important here. This is evidenced by once well-known company names such as Schering, Agfa, Riedel de Haen, Kahlbaum and Kunheim. However, there are only a few traces of this left. This richly illustrated lecture follows these traces of “The Chemical Berlin”. From Kunckel's laboratory on Pfaueninsel to the Bear Pharmacy in the Nikolaiviertel, where several chemical elements were discovered, and to the various locations of chemical institutes and manufacturing plants, the past is compared with what we see today at these places.