Artikel
Palladium‐Catalyzed Formal [4 + 2] Benzannulation of 1‐ferrocenyl‐2‐bromobenzene with Alkynes
Von Wiley-VCH zur Verfügung gestellt
A Pd-catalyzed formal [4 + 2] benzannulation of 1-ferrocenyl-2-bromobenzenes with diarylacetylenes has been developed, delivering various substituted naphtho-ferrocenes.
Abstract
A Pd-catalyzed formal [4 + 2] benzannulation of 1-ferrocenyl-2-bromobenzene with diarylacetylenes involving C─C coupling/C─H functionalization processes are developed, which provides a straightforward access to various substituted naphtho-ferrocenes. This methodology offers a novel and efficient approach to produce polycyclic aromatic hydrocarbons (PAHs). The preliminary investigation shows the chiral phosphine ligand N-Me-PC-Phos has great potential in the asymmetric synthesis of planar naphtho-ferrocene derivatives.
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![Palladium‐Catalyzed Formal [4 + 2] Benzannulation of 1‐ferrocenyl‐2‐bromobenzene with Alkynes](/_next/image?url=https%3A%2F%2Fcdn.gdch.de%2Fprod%2Fnadc20264158499_fig_0001_a_8463b1bf14.png&w=256&q=75)
![Palladium‐Catalyzed Formal [4 + 2] Benzannulation of 1‐ferrocenyl‐2‐bromobenzene with Alkynes](/_next/image?url=https%3A%2F%2Fcdn.gdch.de%2Fprod%2Fnadc20264158504_gra_0001_a_6653df00f8.png&w=256&q=75)
