Highly sensitive glucose electrochemical sensor using sugar‐lectin interactions
Immobilization of glucose oxidase using sugar-lectin interactions on electrode surface and highly sensitive glucose sensor.
Abstract
In this study, glucose oxidase (GOx) was immobilized on the electrode surface by layer-by-layer and gel membrane technique and characterized the GOx immobilized film morphology, H2O2 permeability, and glucose response. Concanavalin A (Con A)-GOx multilayer electrodes showed higher glucose-related current response than GOx-bovine serum albumin gel membrane-coated electrode, a common modification method. The thin thickness of the Con A/GOx multilayer film efficiently catalyzed the enzymatic reaction, and H2O2 was produced near the electrode surface, resulting in an immediate electrode response.




