Vortrag

Catalytic Enantioselective Pictet-Spengler Reaction of Ketones: Development and Applications in the Total Synthesis of Indole Alkaloids

Catalytic Enantioselective Pictet-Spengler Reaction of  Ketones:  Development and Applications in the Total  Synthesis of Indole Alkaloids
Veranstaltungen
20.06.23

15:00 – 16:00

Bonn

Gerhard-Domagk-Str. 1, 53121, Bonn, Deutschland

Professor Jieping Zhu

École Polytechnique Fédérale de Lausanne

The asymmetric Pictect-Spengler reaction (PSR) between tryptamine and aldehydes is now well-developed. Conversely, catalytic enantioselective PSR of ketone is essentially unexploited. In this presentation, we will present our work on the catalytic enantioselective PSR of tryptamine with 1,2-diones, α-ketoesters and α-ketoamide for the synthesis of enantioenriched 1,1-disubstituted tetrahydro-α-carboline (THBC) and their application in the total synthesis of monoterpene indole alkaloids.

Kontaktperson

Prof.Dr. Connie Lu

Prof.Dr. Connie Lu


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Interessen

Organische Chemie
Alle Fachgebiete
Veranstaltungsdetails
20.06.23

15:00 – 16:00

Bonn

Gerhard-Domagk-Str. 1, 53121, Bonn, Deutschland

Professor Jieping Zhu

École Polytechnique Fédérale de Lausanne


Kontaktperson

Prof.Dr. Connie Lu

Prof.Dr. Connie Lu


Zu Ihrem Kalender hinzufügen

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In andere Kalender herunterladen