Artikel
Selective Synthesis of Furan‐3(2H)‐one Fused Seven‐, Eight‐, or Nine‐Membered Ring from the Reaction of Diynone and Cyclic β‐Keto Ester
Von Wiley-VCH zur Verfügung gestellt
A domino reaction of diynone and cyclic β-keto ester has been disclosed. This reaction provides a new strategy for the synthesis of a series of furan-3(2H)-one fused seven-, eight-, or nine-membered ring with good stereoselectivity and atom economy. Mechanistically, this reaction involves sequential Michael addition, intramolecular cyclization, ring opening, isomerization, anti-Michael addition and protonation.
A domino reaction of diynone and cyclic β-keto ester has been disclosed. This reaction provides a new strategy for the synthesis of a series of furan-3(2H)-one fused seven-, eight-, or nine-membered ring with good stereoselectivity and atom economy.
